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Home > Products >  99% Pharmaceutical Raw Material Amorolfine Hydrochloride / Amorolfine HCl CAS 106614-68-0

99% Pharmaceutical Raw Material Amorolfine Hydrochloride / Amorolfine HCl CAS 106614-68-0 CAS NO.106614-68-0

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  • Min.Order: 10 Gram
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    EP/BP/USP(1-10)Metric TonEP/BP/USP(11-100)Metric Ton

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Keywords

  • 106614-68-0
  • 106614-68-0
  • 106614-68-0

Quick Details

  • ProName: 99% Pharmaceutical Raw Material Amorol...
  • CasNo: 106614-68-0
  • Molecular Formula: C21H35NO HCl
  • Appearance: white crystalline powder
  • Application: use in chemical
  • DeliveryTime: within a week
  • PackAge: bags
  • Port: Shanghai
  • ProductionCapacity: 12 Kilogram/Day
  • Purity: 99%
  • Storage: Kept in a well-closed, light-resistant...
  • Transportation: by sea or express
  • LimitNum: 10 Gram
  • Moisture Content: 0.001
  • Impurity: 0.001
  • Water content: 0%

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Details

99% Pharmaceutical Raw Material Amorolfine Hydrochloride / Amorolfine HCl CAS 106614-68-0

 

Basic information

 

Cas No.

78613-38-4

Product ID

A5056

Product Name

Amorolfine Hydrochloride

Chemical Name

(2S,6R)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine hydrochloride

Formula

C21H35NO HCl

Formula Wt.

353.97

Melting Point

204-206

Purity

>98.5%

Solubility

Slightly soluble in water, less soluble in HCl solution

Store Temp

Ambient

 

Description:

Amorolfine is an antifungal compound that prevents ergosterol synthesis through the inhibition of sterol 14α-demethylase. Amorolfine increases release of prostaglandin D2 metabolites, inhibiting release of thromboxane B2 (TxB2), activation of NF-κB, and production of thymic stromal lymphopoetin; as a result, inflammation in atopic dermatitis models is decreased.

COA

 


TEST ITEM


LIMT


TEST RESULTS


APPEARANCE


WHITE OR ALMOST WHITE,HYGROSCOPLE,CRYSTALLINE POWDER


CONFORMS


SOLUBILITY


SLIGHTLY SOLUBLE IN WATER,FREELY SOLUBLE IN METHANOL,SOLUBLE IN ACETONE


COMPLIES


IDENTIFICATION


TO COMPLY


COMPLIES


APPEARANCE OF SOLUTION


THE SOLUTION IS CLEAR AND COLORLESS


COMPLIES


RELATED SUBSTANCES %


IMPURITY A≤0.4
IMPURITY B≤0.3
IMPURITY C≤0.1
UNSPECIFIED IMPURITIES≤0.1
TOTAL IMPURITY≤0.6


0.3
NIL
NIL
0.02
0.32


HEAVY METALS %


≤0.001


<0.001


LOSS ON DRYING %


≤0.5


0.18


SULPHATED ASH %


≤0.1


<0.1


ASSAY (ON DRY BASIS) %


99.0-101.0


99.68


GRANULE SIZE


180 MICRON MAX


CONFORMS


CONCLUSION


CONFORMS TO EP5.6

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