China (Mainland)
Pharmaceutical Caspofungin For Treating certain fungal infections 162808-62-0 CAS NO.162808-62-0
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- Min.Order: 10 Gram
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Quick Details
- ProName: Pharmaceutical Caspofungin For Treatin...
- CasNo: 162808-62-0
- Molecular Formula: C53H89N9O15
- Appearance: white crystalline powder
- Application: use in chemical
- DeliveryTime: within a week
- PackAge: bags
- Port: Shanghai
- ProductionCapacity: 12 Kilogram/Day
- Purity: 99%
- Storage: Kept in a well-closed, light-resistant...
- Transportation: by sea or express
- LimitNum: 10 Gram
- Moisture Content: 0.001
- Impurity: 0.001
- Water content: 0%
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1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so you can trust us. 2, Payment method: for example T/T, Westerm Union,other 3, Excellent Service: Best service and after-sales service to all clients. 1)We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment.. 2)We will ship the goods that you order from us by DHL, UPS, TNT and EUB.We will decided to choose which courier depend on different countries.To find the best way to delivery the goods for you. 3)As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact us immediately. 4,Fast and safe delivery: Sample Order : As usual you can get the goods within 4-7days. We can send it via HKems, HK Air Post, DHL or other methods. We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days. Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our customers and principals. With our high-performance teamwork centers and associated production sites for custom synthesis, we ensure effective professional response and offer extensive applications-related consulting and compliance regulation services. |
Details
Pharmaceutical Caspofungin For Treating certain fungal infections 162808-62-0
Quick detail
| Product Name: | Caspofungin |
| Synonyms: | Caspofungine;CASPOFUNGIN;CASPORFUNGIN;Aids058650;Aids-058650;Cancidas (tm);m991;Caspofungin .CH3COOH |
| CAS: | 162808-62-0 |
| MF: | C53H89N9O15 |
| MW: | 1092.33 |
| EINECS: | |
| Product Categories: | Antifungals |
Caspofungin Introduction
Caspofungin is used for:
Treating certain fungal infections.
Caspofungin is an antifungal agent. It works by weakening fungal cell walls, which allows the cell contents to leak out, resulting in the death of the fungus.
Caspofungin is used to treat a variety of serious fungal infections. It is often used in patients who cannot use or do not respond to other antifungal medications (such asamphotericin B,itraconazole). Caspofungin belongs to a class of drugs known as echinocandins. It works by stopping the growth of fungus.
Caspofungin Dosing & Uses
1. Candida Infections
Includes candidemia and other Candida infections including intra-abdominal abscesses, peritonitis, and pleural space infections
Day 1 loading dose: 70 mg IV infused over 1 hr (as a single dose)
Maintenance: 50 mg IV qDay infused over 1 hr
Continue antifungal therapy for at least 14 days after last positive culture; patients who remain persistently neutropenic may warrant longer course of therapy pending resolution of neutropenia
2. Esophageal Candidiasis
Indicated for treatment of esophageal candidiasis
50 mg IV qDay infused over 1 hr, continue for 7-14 days after symptom resolution
Loading dose not necessary, has not been studied with this indication
May consider suppressive oral therapy in patients with HIV infection because of the risk of oropharyngeal candidiasis relapse
3. Invasive Aspergillosis
Indicated for invasive aspergillosis in patients refractory to or intolerant of other therapies (eg, amphotericin B, itraconazole)
Day 1 loading dose: 70 mg IV infused over 1 hr (as a single dose)
Maintenance: 50 mg IV qDay infused over 1 hr
Duration of treatment should be based upon the severity of the underlying disease, recovery from immunosuppression, and clinical response.
4. Febrile Neutropenia
Empirical therapy for presumed fungal infections in febrile, neutropenic patients
Day 1 loading dose: 70 mg IV infused over 1 hr
Maintenance: 50 mg IV qDay infused over 1 hour; if well tolerated but not achieving adequate response, may increase to 70 mg IV qDay
Duration of treatment should be based on clinical response; continue empirical therapy until resolution of neutropenia
If fungal infection is confirmed, continue therapy for a minimum of 14 days; treatment should continue for at least 7 days after both neutropenia and clinical symptoms are resolved
5. Dosage Modifications
Coadministration with strong CYP inducers (rifampin): 70 mg IV qDay
Coadministration with other drug clearance inducers: Consider increasing to 70 mg IV qDay
6. Hepatic Impairment
Mild Child-Pugh 5-6: No dosage adjustment necessary
Moderate Child-Pugh 7-9: Load 70 mg IV, then 35 mg IV qDay
Severe Child-Pugh >9: Safety and efficacy not established