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Home > Products >  High purity Genistein with best price and good quality

High purity Genistein with best price and good quality CAS NO.446-72-0

  • Min.Order: 10 Gram
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  • Product Details

Keywords

  • Genistein
  • purity 98% Genistein
  • high quality cas 446-72-0

Quick Details

  • ProName: High purity Genistein with best price ...
  • CasNo: 446-72-0
  • Molecular Formula: C15H10O5
  • Appearance: yellow crystalline solid
  • Application: API for anti-tumor, anti-fungal, fat.
  • DeliveryTime: within in 5-7 working days after recei...
  • PackAge: 25kg/paper drum or as customers' requi...
  • Port: Wuhan, Shanghai, Guangzhou, Tianjin po...
  • ProductionCapacity: 250 Kilogram/Month
  • Purity: ≥98%
  • Storage: Keep container tightly closed in a coo...
  • Transportation: by sea/by express
  • LimitNum: 10 Gram
  • Grade: Pharma Grade

Superiority

1, High quality with competitive price:

  We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery

  1) Parcels can be sent out within 24 hours after payment. Tracking number is available.

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3, We have clients throughout the world.

  1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.

  2) Market feedback and goods feedback are appreciated, meeting customers's requirement is our responsibility.

  3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

Details

Basic information

Product Name:

Genistein

Synonyms:

4’,5,7-trihydroxy-isoflavon;5,7-dihydroxy-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-on;c.i.75610;differenola;genistein(synthetic);genisteol;genisterin;prunetol

CAS:

446-72-0

MF:

C15H10O5

MW:

270.24

Product Categories:

pharmacetical;Biochemistry;Flavonoids;Natural Plant Extract;The group of Daidzin;Inhibitors;Tyrosine Kinase Inhibitors;Protein Kinase;Signalling;Plant extract;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;standardized herbal extract;inhibitor

Mol File:

446-72-0.mol

Genistein Structure

 

Chemical Properties

melting point 

297-298 °C

boiling point 

555.5 °C at 760 mmHg

density 

1.548 g/cm3

flashing point 

217.1 °C

vapor pressure 

6E-13 mmHg at 25°C

storage temp. 

−20°C

solubility 

DMSO: soluble

Water Solubility 

insoluble

Stability

Light Sensitive

 

Usage And Synthesis

Chemical Properties

Yellow Crystalline Solid

Usage

Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol

Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.

cytotoxic inhibitor of tyrosine kinase and topoisomerase II kinase

 

About us:

Hubei Jusheng Technology Co., Ltd., is a large group corporation which engaged in the R&D and manufacture of chemicals, Pharmaceuticals and intermediates. We have earned ourselves a good reputation at home and abroad with advanced technology, standardized management and well established service systerm. We have developed to a very famous group corporation Enterprise in chemical industry step by step. 

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