- Product Details
Keywords
- Deserpidine
- purity 99% Deserpidine
- high quality cas 131-01-1
Quick Details
- ProName: High purity Deserpidine with best qual...
- CasNo: 131-01-1
- Molecular Formula: C32H38N2O8
- Appearance: White crystalline powder
- Application: Antihypertensive
- DeliveryTime: within in 5-7 working days after recei...
- PackAge: 25kg/paper drum or as customers' requi...
- Port: Wuhan, Shanghai, Guangzhou, Tianjin po...
- ProductionCapacity: 200 Kilogram/Month
- Purity: ≥99%
- Storage: sealed and stored in light-tight, shad...
- Transportation: by sea/by express
- LimitNum: 10 Gram
- Quality Standard: Enterprise Standard
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Details
Basic information
Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
Product Name: |
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Synonyms: |
methyl 17-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate;DESERPIDINE;Canescine;Harmonyl;Raunormine;Recanescine;Reserpidine;(1S,2R,3R,4aS,13bR,14aS)-2-methoxy-3-(3,4,5-trimethoxybenzoyl)oxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2-a]$b-carboline-1-carboxylic acid methyl ester |
CAS: |
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MF: |
C32H38N2O8 |
MW: |
578.65272 |
Mol File: |
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Pharmacology |
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Indication |
For the treatment of hypertension. |
Pharmacodynamics |
Deserpidine, an alkaloid of Rauwolfia canescens, is used as an antihypertensive. Rauwolfia alkaloids work by controlling nerve impulses along certain nerve pathways. As a result, they act on the heart and blood vessels to lower blood pressure. |
Mechanism of action |
Deserpidine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the sequestering of neurotransmitters into storage vesicles located in the presynaptic neuron. The neurotransmitters that are not sequestered in the storage vesicle are readily metabolized by monoamine oxidase (MAO) causing a reduction in catecholamines. |
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