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Home > Products >  Entecavir Oral Antiviral Raw Materia Drug CAS 142217-69-4 Treatment of Hepatitis B

Entecavir Oral Antiviral Raw Materia Drug CAS 142217-69-4 Treatment of Hepatitis B CAS NO.142217-69-4

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Quick Details

  • ProName: Entecavir Oral Antiviral Raw Materia D...
  • CasNo: 142217-69-4
  • Molecular Formula: C12H15N5O3
  • Appearance: white crystalline powder
  • Application: use in chemical
  • DeliveryTime: within a week
  • PackAge: bags
  • Port: Shanghai
  • ProductionCapacity: 12 Kilogram/Day
  • Purity: 99%
  • Storage: Kept in a well-closed, light-resistant...
  • Transportation: by sea or express
  • LimitNum: 10 Gram
  • Moisture Content: 0.001
  • Impurity: 0.001
  • Water content: 0%

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Details

Entecavir Oral Antiviral Raw Materia Drug CAS 142217-69-4 Treatment of Hepatitis B

 

Quick detail


Entecavir
CAS No.: 142217-69-4
Synonyms: 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one; Baraclude; UNII-NNU2O4609D; Entecavir(anhydrous);
Formula: C12H15N5O3
Exact Mass: 277.11700
Molecular Weight: 277.27900
PSA: 130.05000
LogP: -0.24660
Properties
Appearance white to off-white/yellow crystalline powder
Density: 1.81g/cm3
Melting Point: 249-252ºC
Boiling Point: 734.2ºC at 760 mmHg
Flash Point: 397.9ºC
Refractive Index: 1.837

 

Entecavir Description


Entecavir INN, abbreviated ETV, is an oral antiviral drug used in the treatment of hepatitis B virus (HBV) infection. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. More specifically, it is a deoxyguanosine analogue belonging to a class of carbocyclic nucleosides, that inhibits reverse transcription, DNA replication and transcription in the viral replication process.

 

Entecavir is used for


Treating HBV infection in certain patients.

Entecavir is a nucleoside analogue. It works by reducing the amount of HBV in the blood. It also helps prevent the HBV from multiplying and infecting new liver cells.

 

Do NOT use entecavir if


you are allergic to any ingredient in entecavir
you have HIV infection and you are not receiving HAART

Contact your doctor or health care provider right away if any of these apply to you.

 

Entecavir Dosage


Recommended dosage: adult and over the age of 16 young oral this product, once a day, each 0.5 mg. lamivudine treatment viremia or patients with lamivudine resistant mutants to once a day, each 1.0 mg (0.5mg two pieces), taken on an empty stomach (a meal or a meal after at least 2 hours).


How Does Entecavir Work


Entecavir is a reverse transcriptase inhibitor that works by preventing the hepatitis B virus from multiplying and thereby decreasing the amount of the virus in the body.


However, it is important to note that entecavir is not a cure for HBV and it may not prevent damage to the liver or reduce the chances of developing liver cancer. In addition, entecavir doesn't prevent the spread of HBV to others through the normal routes of transmission, including sexual contact or exposure to blood or bodily fluids.


Side Effects of Entecavir


As with all drugs, there are some risks to taking entecavir. Some are more serious than others.


Lactic Acidosis In rare cases, entecavir can cause a condition known as lactic acidosis, which is a build-up of lactic acid in the body. This condition can come on insidiously and worsen over time, therefore even mild symptoms warrant seeking emergency medical help.

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