- Product Details
Keywords
- Aprepitant
- purity 99% Aprepitant
- high quality cas 170729-80-3
Quick Details
- ProName: High purity Aprepitant with best price...
- CasNo: 170729-80-3
- Molecular Formula: C23H21F7N4O3
- Appearance: off-white to light yellow cyrstalline ...
- Application: API
- DeliveryTime: within in 5-7 working days after recei...
- PackAge: 25kg/paper drum or as customers' requi...
- Port: Wuhan, Shanghai, Guangzhou, Tianjin po...
- ProductionCapacity: 200 Kilogram/Week
- Purity: ≥99%
- Storage: stored at dry, cool and avoid light
- Transportation: by sea/by express
- LimitNum: 10 Gram
- Grade: Pharma Grade
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Details
Basic information
Product Name: |
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Synonyms: |
5-[2(r)-[1(r)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(s)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2h-1,2,4-triazol-3-one;aprepitant;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one, Emend;5-[2(R)-[1(R)-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2H-1,2,4-triazol-3-one;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;Emend;MK-0869 |
CAS: |
|
MF: |
C23H21F7N4O3 |
MW: |
534.4266624 |
Product Categories: |
Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Aprepitant;Inhibitors |
Mol File: |
|
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Chemical Properties |
melting point |
244-246°C |
density |
1.51 g/cm3 |
storage temp. |
-20°C Freezer |
Usage And Synthesis |
Chemical Properties |
Off-White to Light Yellow Cyrstalline Solid |
Usage |
A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. |
anticholinergic |
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