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Best price and high quality Sevoflurane CAS NO.28523-86-6
- Min.Order: 10 Gram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- Sevoflurane
- High purity Sevoflurane
- high quality cas 28523-86-6
Quick Details
- ProName: Best price and high quality Sevofluran...
- CasNo: 28523-86-6
- Molecular Formula: C4H3F7O
- Appearance: White crystalline powder
- Application: anesthetics, the physical, pharmacodyn...
- DeliveryTime: within in 5-7 working days after recei...
- PackAge: 25kg/drum or as customers' requirement...
- Port: Wuhan, Shanghai, Guangzhou, Tianjin po...
- ProductionCapacity: 200 Kilogram/Month
- Purity: ≥99%
- Storage: Room temperature (15 to 30°C ). Keep c...
- Transportation: by sea/by express
- LimitNum: 10 Gram
- Moisture Content: ≤5%
Superiority
Details
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Name |
Sevoflurane |
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Accession Number |
DB01236 (APRD00219) |
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Type |
Small Molecule |
|
Groups |
Approved, Vet Approved |
|
Description |
Sevoflurane (2,2,2-trifluoro-1-[trifluoromethyl]ethyl fluoromethyl ether), also called fluoromethyl, is a sweet-smelling, non-flammable, highly fluorinated methyl isopropyl ether used for induction and maintenance of general anesthesia. Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology. [Wikipedia] |
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Structure |
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Description |
This compound belongs to the class of organic compounds known as dialkyl ethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups. |
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Pharmacology |
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Indication |
Used for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery. |
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Pharmacodynamics |
Sevoflurane (also called fluoromethyl) is a halogenated ether used for induction and maintenance of general anesthesia. Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology. It is often administered in nitrous oxide and pure oxygen. After desflurane it is the volatile anesthetic with the fastest onset and offset. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential. |
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Mechanism of action |
Sevoflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Sevoflurane also activates calcium dependent ATPase in the sarcoplasmic reticulum by increasing the fluidity of the lipid membrane. It also appears to bind the D subunit of ATP synthase and NADH dehydogenase and also binds to the GABA receptor, the large conductance Ca2+ activated potassium channel, the glutamate receptor, and the glycine receptor. |
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Absorption |
Rapidly absorbed into circulation via the lungs, however solubility in the blood is low. |
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