China (Mainland)
Environmental friendly Sulfadimidine for staphylococcus CAS NO.57-68-1
- Min.Order: 10 Gram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- Sulfadimidine
- purity 99% Sulfadimidine
- high quality cas 57-68-1
Quick Details
- ProName: Environmental friendly Sulfadimidine f...
- CasNo: 57-68-1
- Molecular Formula: C12H14N4O2S
- Appearance: A white or light yellow crystal powder
- Application: Sulfa antibiotic anti-inflammatory dru...
- DeliveryTime: within in 5-7 working days after recei...
- PackAge: 25kg/barrel or as customers' requireme...
- Port: Wuhan, Shanghai, Guangzhou, Tianjin po...
- ProductionCapacity: 200 Kilogram/Month
- Purity: ≥98.5%
- Storage: In dark, dry firmly sealed place
- Transportation: by sea/by express
- LimitNum: 10 Gram
Superiority
Details
|
Identification |
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|---|---|
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Name |
Sulfamethazine |
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Chemical name |
N1-(4,6-Dimethyl-2-pyrimidinyl)sulfanilamide |
|
Type |
Small Molecule |
|
Groups |
Approved, Vet Approved |
|
Description |
A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides. |
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Structure |
 |
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Pharmacology |
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|---|---|
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Indication |
For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections. |
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Pharmacodynamics |
Sulfamethazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamethazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA. |
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Mechanism of action |
Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides. |
|
Absorption |
Rapidly absorbed following oral administration. |
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