China (Mainland)
High purity Pyrimethamine for antifungal drugs with good quality CAS NO.58-14-0
- Min.Order: 10 Gram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- Pyrimethamine
- purity 99% Pyrimethamine
- high quality cas 58-14-0
Quick Details
- ProName: High purity Pyrimethamine for antifung...
- CasNo: 58-14-0
- Molecular Formula: C12H13ClN4
- Appearance: white solid
- Application: Antifungal Drugs
- DeliveryTime: within in 5-7 working days after recei...
- PackAge: 25kg/paper drum or as customers' requi...
- Port: Wuhan, Shanghai, Guangzhou, Tianjin po...
- ProductionCapacity: 250 Kilogram/Month
- Purity: ≥99%
- Storage: Keep container tightly closed in a coo...
- Transportation: by sea/by express
- LimitNum: 10 Gram
- Grade: Pharma Grade
- Standard: BP2000.98/USP25.27
Superiority
1, High quality with competitive price:
We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcels can be sent out within 24 hours after payment. Tracking number is available.
2) Secure and discreet shipment. You have various choices of transportation methods.
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
2) Market feedback and goods feedback are appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
Details
Basic information
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Product Name: |
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Synonyms: |
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine;2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine;2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-;2,4-Pyrimidinediamine, 5-(p-chlorophenyl)-6-ethyl-;2,4-Pyrimidinediamine,5-(4-chlorophenyl)-6-ethyl-;4753 R.P.;4753r.p.;5-(4’-chlorophenyl)-2,4-diamino-6-ethylpyrimidine |
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CAS: |
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MF: |
C12H13ClN4 |
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MW: |
248.71 |
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Product Categories: |
APIs & Intermediate;Pyrimidine;Organics;Amines;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Inhibitor;Heterocycle-Pyrimidine series;DARAPRIM |
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Mol File: |
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Chemical Properties |
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melting point |
233-234°C |
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boiling point |
491.5 °C at 760 mmHg |
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density |
1.305 g/cm3 |
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flashing point |
251 °C |
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vapor pressure |
8.34E-10 mmHg at 25°C |
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storage temp. |
0-6°C |
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Water Solubility |
<0.01 g/100 mL at 21 ºC |
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Stability |
Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents. |
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Usage And Synthesis |
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Chemical Properties |
White Solid |
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Usage |
Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial |
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For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine |
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Air & Water Reactions |
Insoluble in water. |
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Reactivity Profile |
Pyrimethamine is sensitive to exposure to light . Neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
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Fire Hazard |
Flash point data for Pyrimethamine are not available; however, Pyrimethamine is probably combustible. |
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Biological Activity |
Potent inhibitor of multi-drug and toxin extrusion (MATE) transporters (K i values are 46 and 77 nM for human MATE2-K-HEK293 and MATE1-HEK293 cells respectively). Also inhibits dihydrofolate reductase (DHFR). |
About us:
Hubei Jusheng Technology Co., Ltd., is a large group corporation which engaged in the R&D and manufacture of chemicals, Pharmaceuticals and intermediates. We have earned ourselves a good reputation at home and abroad with advanced technology, standardized management and well established service systerm. We have developed to a very famous group corporation Enterprise in chemical industry step by step.
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