China (Mainland)
High purity Teichomycin A2 with best quality CAS NO.61036-64-4
- Min.Order: 10 Gram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- Teichomycin A2
- purity 99% Teichomycin A2
- high quality cas 61036-64-4
Quick Details
- ProName: High purity Teichomycin A2 with best q...
- CasNo: 61036-64-4
- Molecular Formula: C78H77C12N8O32R
- Appearance: white powder
- Application: API
- DeliveryTime: within in 5-7 working days after recei...
- PackAge: 25kg/tin or as customers' requirements
- Port: Wuhan, Shanghai, Guangzhou, Tianjin po...
- ProductionCapacity: 200 Kilogram/Month
- Purity: ≥99%
- Storage: Guard against damp, Keep away from the...
- Transportation: by sea/by express
- LimitNum: 10 Gram
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Details
Basic information
Teicoplanin is a glycopeptide antibiotic. It is a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). All teicoplanins share a same glycopeptide core, termed teicoplanin A3-1, a fused ring structure to which two carbohydrates (mannose and N-acetylglucosamine) are attached. The major and minor components also contain a third carbohydrate moiety, β-D-glucosamine, and differ only by the length and conformation of a side chain attached to it.
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Product Name: |
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Synonyms: |
teicoplanin a2;teichomycina2 |
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CAS: |
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MF: |
C78H77Cl2N8O32R |
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MW: |
1709.39 |
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Pharmacology |
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Indication |
For the treatment of bacterial infections caused by susceptible microorganisms. |
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Pharmacodynamics |
Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus andEnterococcus faecalis. It is a glycopeptide antiobiotic extracted from Actinoplanes teichomyceticus, with a similar spectrum of activity to vancomycin. Its mechanism of action is to inhibit bacterial cell wall synthesis. Oral teicoplanin has been demonstrated to be effective in the treatment of pseudomembranous colitis and Clostridium difficile-associated diarrhoea, with comparable efficacy to vancomycin. |
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Mechanism of action |
Teicoplanin inhibits peptidoglycan polymerization, resulting in inhibition of bacterial cell wall synthesis and cell death. |
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Absorption |
Teicoplanin is poorly absorbed after oral administration but is 90% bioavailable when administered intramuscularly. |
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