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Home > Products >  Pharmaceutical Ingredients Omeprazole (CAS :73590-58-6)

Pharmaceutical Ingredients Omeprazole (CAS :73590-58-6) CAS NO.73590-58-6

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  • Min.Order: 10 Gram
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  • Product Details

Keywords

  • 73590-58-6
  • 73590-58-6
  • 73590-58-6

Quick Details

  • ProName: Pharmaceutical Ingredients Omeprazole ...
  • CasNo: 73590-58-6
  • Molecular Formula: C17H19N3O3S
  • Appearance: white crystalline powder
  • Application: use in chemical
  • DeliveryTime: within a week
  • PackAge: bags
  • Port: Shanghai
  • ProductionCapacity: 12 Kilogram/Day
  • Purity: 99%
  • Storage: Kept in a well-closed, light-resistant...
  • Transportation: by sea or express
  • LimitNum: 10 Gram
  • Moisture Content: 0.001
  • Impurity: 0.001
  • Water content: 0%

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Details

Product Description

Pharmaceutical Ingredients Omeprazole (CAS :73590-58-6)

Basic information:
                                  Omeprazole
English Name Omeprazole
Synonyms 1h-benzimidazole,5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulf;
2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine;5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazol;audazol;aulcer;belmazol;ceprandal;elgam
CAS 73590-58-6
Molecular formula C17H19N3O3S
Molecular weight 345.42
Categories Drug bulk;Active Pharmaceutical Ingredients;Omeprazole;Intermediates & Fine Chemicals; Pharmaceuticals;API's;ATPase
Quality standard company standard / in house
Assay more than 98%
Unit KG
Package 25 kilograms of bucket
Chemical Properties White Crystalline Solid
Usage Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative

Applications: 

>Omeprazole is one of the most widely prescribed drugs internationally and is available over-the-counter in some countries. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. 

>Omeprazole can be used in the treatment of gastroesophageal reflux disease, peptic ulcers, erosive esophagitis, and Zollinger-Ellison syndrome. 

>Gastroesophageal reflux disease: Gastroesophageal reflux disease (GERD) is a chronic condition in which acidic stomach content leaks back into the esophagus and irritates it. It may cause heartburn, which is a painful burning feeling in the chest or throat. 

>Peptic ulcers: Peptic ulcers are sores that develop in the lining of either the stomach or the duodenum due to damage from stomach acid. The most common cause of a peptic ulcer is infection by Helicobacter pylori. Another major cause of a peptic ulcer is long term usage of non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen. Treatment of Helicobacter pylori infection can be completed by taking a triple therapy combination of omeprazole,  for 7-14 days. 

>Erosive esophagitis: Erosive esophagitis is due to tissue damage to the lining of the esophagus, because of inflammation or irritation over time. It may be caused by acid reflux from GERD, infection by a virus or fungus, an autoimmune disorder, certain medications, or alcohol abuse. 

COA:
 



Items


Standard


Results


Appearance


White or almost white powder


Conforms


Identification
A.Thin-layer chromatography
B. IR spectrophotometry


Rf value of the principal spot observed in the chromatogram of test solution corresponds to that of the pricipal spot observed in the chromatogram of standard solution
IR spectrum of omeprazole sample corresponds to that of omeprazole RS.


Conforms
 
Conforms


Completeness of solution


Clear


Conforms


Color of solution


The absorbance at 440 nm is not greater than 0.10


0.01


Loss on drying


≤0.5%


0.03%


Residue on ignition


≤0.1%


0.09%


Heavy metals


0.002%


<0.002%


Residual solvents
Methylene chloride
Methanol
Acetone 


≤600ppm
≤3000ppm
≤5000ppm


76ppm
164ppm
130ppm


Chromatographic purity
Any individual impurity
Total impurities


≤0.3%
≤1.0%


0.04%
0.11%


Microbial limits
Bacteria
Total molds and yeasts
Controlled bacteria


≤500 CFU/g
≤50 CFU/g
Absence


<10 CFU/g
<10 CFU/g
Undetectable


Assay


98.0%-102.0%


100.9%


Partical size


 ≥85%(≤15um)


96.1%


Conclusion


Conforming to USP 36 and in-house requirements.        .

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