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Home > Products >  Raw Material Antineoplastic API Tamsulosin Hydrochloride CAS 106463-17-6

Raw Material Antineoplastic API Tamsulosin Hydrochloride CAS 106463-17-6 CAS NO.106463-17-6

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Keywords

  • 106463-17-6
  • 106463-17-6
  • 106463-17-6

Quick Details

  • ProName: Raw Material Antineoplastic API Tamsul...
  • CasNo: 106463-17-6
  • Molecular Formula: C20H28N2O5S.HCl
  • Appearance: white crystalline powder
  • Application: use in chemical
  • DeliveryTime: within a week
  • PackAge: bags
  • Port: Shanghai
  • ProductionCapacity: 12 Kilogram/Day
  • Purity: 99%
  • Storage: Kept in a well-closed, light-resistant...
  • Transportation: by sea or express
  • LimitNum: 10 Gram
  • Moisture Content: 0.001
  • Impurity: 0.001
  • Water content: 0%

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Details

Raw Material Antineoplastic API Tamsulosin Hydrochloride CAS 106463-17-6

 

1. Quick Details:

 

Product name: Tamsulosin hydrochloride

Synonyms:Benzenesulfonamide,5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-,monohydrochloride (9CI);Benzenesulfonamide,5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, monohydrochloride,(R)-;(-)-YM 12617;(R)-(-)-YM 12617;Flomax;Harnal;LY 253351;Omic;Omnic;YM 12617-1;YM 617;Yutanal;Tamsulosin HCl;

CAS Number:106463-17-6

Appearance: white to off-white solid

Assay: 99%

Molecular weight: 444.97

Molecular Formula: C20H28N2O5S.HCl

Melting Point: 228-230 °C

Boiling Point: 595.5 °C at 760 mmHg

Flash Point:313.9 °C

Using: Used in the treatment of prostate hyperplasia.

 

2. Product Description:

 

Tamsulosin is a selective α1 receptor antagonist that has preferential selectivity for the α1A receptor in the prostate versus the α1B receptor in the blood vessels.

When alpha 1 receptors in the bladder neck and the prostate are blocked, this causes a relaxation in smooth muscle and therefore less resistance to urinary flow. Due to this the pain associated with BPH can be reduced.

 

3. Application:

 

It is used in the treatment of difficult urination, a common symptom of enlarged prostate. Tamsulosin, and other medications in the class called alpha blockers, work by relaxing bladder neck muscles and muscle fibers in the prostate itself and make it easier to urinate.

 

4. Specification:

 

Items

Specification

Characteristics

White or almost white crystalline powder,

Slightly soluble in water, freely soluble in formic acid,slightly soluble in anhydrous ethanol.

Melting point

about 230°C

Identification

1) should conformed

2) specific rotation: -17.5° to -20.5°

3) examine by infrared absorption spectrophotometry,compare the spectrum obtained with reference spectrum:should meet the requirements

4) should conformed

Related substances

Method A (EP method):

Largest single impurity should ≤0.1%

Method B(EP method):

Largest single impurity should≤0.1%

Total impurities should ≤0.2%

Enantiomeric purity

≤0.1%

Heavy metals

≤20ppm

Loss on drying

≤0.5%

Sulphated ash

≤0.1%

Assay

98.5% ~ 101.0%

 

 

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