High purity Tenofovir with best price CAS NO.147127-20-6

Product Name:

Tenofovir

Synonyms:

1-(6-aminopurin-9-yl)propan-2-yloxymethylphosphonic acid;D,L-TENOFOVIR;TENOFOVIR;(R)-9-(2-PHOSPHONYLMETHOXYPROPYL)-ADENINE;(R)-9-(2-Phosphonomethoxypropyl)Adenine;Tenofovir(ForResearchOnly);(R)-PMPA;[[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid

CAS:

147127-20-6

MF:

C9H14N5O4P

MW:

287.21

Product Categories:

Purine;ACTIVE PHARMACEUTICAL INGREDIENTS;Nucleotides and Nucleosides;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;Inhibitors

Mol File:

147127-20-6.mol

Chemical Properties

melting point 

276-280°C

storage temp. 

Store at -20°C

Water Solubility 

13.4 mg/mL (25 ºC)

Usage And Synthesis

Indications

Tenofovir is indicated for the treatment of HIV, HBV infection. This product also can cooperated with other reverse transcriptase inhibitors for HIV-1 infection and hepatitis B treatment.

Chemical Properties

White Crystalline Solid

Usage

Acyclic phosphonate nucleotide analogue. Used as an anti-HIV agent

Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.

Tenofovir blocks reverse transcriptase and hepatitis B virus infections.

Biological Activity

Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase). Prevents cytotoxicity in SIV-infected C-8166 cells in vitro (IC 50 = 1.5 μ M). Antiviral agent.