China (Mainland)
Vortioxetine (Lu AA21004) HBr New Anti Depressant Powder CAS 508233-74-7 Medicine CAS NO.508233-74-7
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Quick Details
- ProName: Vortioxetine (Lu AA21004) HBr New Anti...
- CasNo: 508233-74-7
- Molecular Formula: C18H22N2S
- Appearance: white crystalline powder
- Application: use in chemical
- DeliveryTime: within a week
- PackAge: bags
- Port: Shanghai
- ProductionCapacity: 12 Kilogram/Day
- Purity: 99%
- Storage: Kept in a well-closed, light-resistant...
- Transportation: by sea or express
- LimitNum: 10 Gram
- Moisture Content: 0.001
- Impurity: 0.001
- Water content: 0%
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1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so you can trust us. 2, Payment method: for example T/T, Westerm Union,other 3, Excellent Service: Best service and after-sales service to all clients. 1)We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment.. 2)We will ship the goods that you order from us by DHL, UPS, TNT and EUB.We will decided to choose which courier depend on different countries.To find the best way to delivery the goods for you. 3)As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact us immediately. 4,Fast and safe delivery: Sample Order : As usual you can get the goods within 4-7days. We can send it via HKems, HK Air Post, DHL or other methods. We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days. Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our customers and principals. With our high-performance teamwork centers and associated production sites for custom synthesis, we ensure effective professional response and offer extensive applications-related consulting and compliance regulation services. |
Details
Vortioxetine (Lu AA21004) HBr New Anti Depressant Powder CAS 508233-74-7 Medicine
Quick detail
| Name: | Vortioxetine (Lu AA21004) |
| CAS No.: | 508233-74-7 |
| Formula: | C18H22N2S |
| Molecular Weight: | 298.45 |
| Synonyms: | 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine;Lu AA 21004; |
| Density: | 1.164 g/cm3 |
| Boiling Point: | 424.833 °C at 760 mmHg |
| Flash Point: | 210.732 °C |
| Product Categories: | 5-HT antagonist;Serotonin transporter inhibitor;Inhibitors |
Vortioxetine Description
Vortioxetine is used to treat depression. Vortioxetine is in a class of medications called serotonin modulators. It works mainly by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
Vortioxetine is considered a new multimodal antidepressant. It has demonstrated antagonistic properties at 5-HT3A and 5-HT7 receptors, partial agonistic properties at 5-HT1B receptors, agonistic properties at 5-HT1A receptors, and potent inhibition of the serotonin reuptake transporter. Of note, preclinical data suggest that these multiple (and in combination) unique effects on numerous serotonin receptors result in regional increases in noradrenaline and dopamine as well as glutamatergic transmission.
Vortioxetine Recomended Dose
The recommended starting dose is 10 mg administered orally once daily without regard to meals.
The dose should then be increased to 20 mg/day, as tolerated.
Consider 5 mg/day for patients who do not tolerate higher doses .
Vortioxetine can be discontinued abruptly. However, it is recommended that doses of 15 mg/day or 20 mg/day be reduced to 10 mg/day for one week prior to full discontinuation if possible.
The maximum recommended dose is 10 mg/day in known CYP2D6 poor metabolizers.
How should this medicine be used
Vortioxetine comes as a tablet to take by mouth. It is usually taken with or without food once a day.
Take vortioxetine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take vortioxetine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor may adjust your dose of vortioxetine depending on how well you respond to treatment and whether you experience side effects. Be sure to talk to your doctor about how you are feeling during your treatment with vortioxetine.
It may take 2 to 4 weeks or longer before you feel the full benefit of vortioxetine. Continue to take vortioxetine even if you feel well. Do not stop taking vortioxetine without talking to your doctor. If you suddenly stop taking vortioxetine, you may experience side effects including headache, muscle stiffness, mood swings, outbursts of anger, dizziness, or runny nose. Your doctor may decrease your dose gradually.
Vortioxetine COA:
| Tests | Specifications | Results |
| Characters | White to off-white crystalline powder with a characteristic sulfide-like order | Complies |
| Identification | IR:similar to Reference Standard | Complies |
| Appearance of solution | Clear and colorless | Complies |
| Specific Rotation | -127°to -132° | -131° |
| Loss on Drying | ≤0.5% | 0.06% |
| Sulphated Ash | ≤0.2% | 0.03% |
| Heavy metals | ≤0.002% | Complies |
| pH | 2.0 to 2.6 | 2.3 |
| Related Compouds |
1. Single Impurity ≤1.0% 2. Sum of Impurity≤2.0% |
Undetected Undetected |
| Assay(Anhydrous) | 98.0% to 101.5% | 100.2% |