China (Mainland)
Gastro-kinetic drugs Chemical Domperidone BP STANDARD CAS NO.57808-66-9
- FOB Price: USD: 1.00-2.00 /Metric Ton Get Latest Price
- Min.Order: 10 Gram
- Payment Terms: T/T,Other
- Available Specifications:
EP/BP/USP(1-10)Metric TonEP/BP/USP(11-100)Metric Ton
- Product Details
Keywords
- Domperidone
- Domperidone supplier
- 57808-66-9
Quick Details
- ProName: Gastro-kinetic drugs Chemical Domperid...
- CasNo: 57808-66-9
- Molecular Formula: C22H24ClN5O2
- Appearance: White crystallized powder
- Application: medical intermediate
- DeliveryTime: Wihtin 5-7 Days
- PackAge: A variety of packing ways for your cho...
- Port: Wuhan / Shanghai / Guangzhou ...
- ProductionCapacity: 500 Kilogram/Month
- Purity: 99%
- Storage: Kept in a well-closed, light-resistant...
- Transportation: EMS, HKEMS, DHL, TNT, UPS, Fedex....
- LimitNum: 10 Gram
- Moisture Content: 0.001
- Impurity: 0.001
Superiority
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1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so you can trust us. 2, Payment method: for example T/T, Westerm Union,other 3, Excellent Service: Best service and after-sales service to all clients. 1)We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment.. 2)We will ship the goods that you order from us by DHL, UPS, TNT and EUB.We will decided to choose which courier depend on different countries.To find the best way to delivery the goods for you. 3)As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact us immediately. 4,Fast and safe delivery: Sample Order : As usual you can get the goods within 4-7days. We can send it via HKems, HK Air Post, DHL or other methods. We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days. Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our customers and principals. With our high-performance teamwork centers and associated production sites for custom synthesis, we ensure effective professional response and offer extensive applications-related consulting and compliance regulation services. |
Details
Domperidone Basic information
Gastro-kinetic drugs Chemical Properties Uses Production method
Product Name: Domperidone
Synonyms: 2h-benzimidazol-2-one,1,3-dihydro-5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1h-benzi;5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidaz;kw-5338;midazol-1-yl)propyl)-4-piperidinyl)-;
DOMPERIDONE;4-(5-chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine;ALPHA-[2-(DIISOPROPYLAMINO)ETHYL]-ALPHA-PHENYL-2-PYRIDINE-ACETAMIDE;5-CHLORO-1-[1-[3-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)PROPYL]-4-PIPERIDINYL]-1,3-DIHYDRO-2H-BENZ-IMIDAZOL-2-ONE
CAS: 57808-66-9
MF: C22H24ClN5O2
MW: 425.91
EINECS: 260-968-7
Product Categories:Dopamine receptor;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labelled Compounds;VIOXX;Other APIs
Uses:
It is a kind of potent peripheral dopamine receptor antagonist with anti-vomiting and gastro-kinetic effects.
It can affect the gastrointestinal motility to make the motility and tension of upper gastrointestinal tract return to normal and promote gastric emptying,
enhancing the antral and duodenal motility, and coordinating the pyloric contraction.
It can be used for the treatment of dyspepsia, and the nausea and vomiting induced by functional, organic, infection, dietary, radiation therapy or drug therapy.
Because it almost has no inhibitory effect on dopamine receptor, there are no psychiatric and neurological side effects. And it can be used for treating the nausea caused by treating the Parkinson’s disease through taking dopamine agonists.
It can be used as anticholinergic antispasmodics.
Domperidone is a kind of phenyl imidazole compounds with a strong role in promoting gastric motility and antiemetic effect. It can strengthen the tension of the sphincter of the lower part of the esophagus, preventing the stomach - esophageal reflux, enhancing the gastric motility,
promoting the gastric emptying, coordinating the stomach and duodenal motility, suppressing nausea, vomiting, and effectively preventing the bile reflux without affecting the secretion of gastric juice.
This product is a kind of peripheral dopamine receptor antagonists which can directly block the gastrointestinal dopamine receptors and exhibit the stimulating effect of gastric motility.
It can enhance the esophageal peristalsis and the tension of esophageal sphincter. Because of its poor penetration through the blood brain barrier, it has almost no antagonism against the dopamine receptor of the brain,
and therefore can excluding the side effects of the spirit and the central nervous system.
