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Phenacetin Pharmaceutical Chemical Anesthetic Anodyne Powder Phenacetin 62-44-2 CAS NO.62-44-2
- Min.Order: 10 Gram
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- Product Details
Keywords
- Phenacetin
- Phenacetin 62-44-2
- 62-44-2
Quick Details
- ProName: Phenacetin Pharmaceutical Chemical Ane...
- CasNo: 62-44-2
- Molecular Formula: 62-44-2
- Appearance: White crystallized powder
- Application: medical intermediate
- DeliveryTime: Wihtin 5-7 Days
- PackAge: A variety of packing ways for your cho...
- Port: Wuhan / Shanghai / Guangzhou ...
- ProductionCapacity: 500 Kilogram/Month
- Purity: 99%
- Storage: Kept in a well-closed, light-resistant...
- Transportation: EMS, HKEMS, DHL, TNT, UPS, Fedex....
- LimitNum: 10 Gram
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Details
99% Pharmaceutical Chemical Anesthetic Anodyne Powder Phenacetin 62-44-2
Phenacetin is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenacetin.
CAS No. 62-44-2
Chemical Name: Phenacetin
Synonyms: Kafa;Soma;Dasin;Fenia;Malex;Tacol;Viden;Xaril;Anapac;Fenina
CBNumber: CB6141828
Molecular Formula: 62-44-2
Formula Weight: 179.22
MOL File: 62-44-2.mol
Phenacetin Property
mp : 133-136 °C(lit.)
bp : 132 °C / 4mmHg
storage temp. : 2-8°C
form : white powder
Water Solubility : 0.076 g/100 mL
Sensitive : Hygroscopic
Merck : 14,7204
BRN : 1869238
Stability : Stable. Incompatible with strong oxidizing agents, strong acids.
Description
DNP (2, 4-DNP, or simply DNP) is an organic compound with the formula HOC6H3(NO2)2. It is a yellow, crystalline solid that has a sweet, musty odor. It sublimes, is volatile with steam, and is soluble in most organic solvents as well as aqueous alkaline solutions.
It is a precursor to other chemicals and is biochemically active, inhibiting energy (ATP) production in cells with mitochondria and was once used as a diet aid.
It is produced by hydrolysis of 2, 4-dinitrochlorobenzene.
Use ：Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.
Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent's APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)). It was also banned in India. As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin's carcinogenicity.
Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.
Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.