99% Pharmaceutical Raw Materials CAS 859-18-7 Lincomycin Hydrochloride CAS NO.859-18-7
- FOB Price: USD: 1.00-2.00 /Metric Ton Get Latest Price
- Min.Order: 10 Gram
- Payment Terms: T/T,
- Available Specifications:
EP/BP/USP(1-10)Metric TonEP/BP/USP(11-100)Metric Ton
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Keywords
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Quick Details
- ProName: 99% Pharmaceutical Raw Materials CAS 8...
- CasNo: 859-18-7
- Molecular Formula: C18H34N2O6S. HCl
- Appearance: white powder
- Application: API
- DeliveryTime: Within 5 days after payment
- PackAge: as request
- Port: Wuhan / Shanghai / Guangzhou ...
- ProductionCapacity: 100 Metric Ton/Month
- Purity: 99%
- Storage: dry, dark and ventilated place
- Transportation: EMS, HKEMS, DHL, TNT, UPS, Fedex.... ...
- LimitNum: 10 Gram
- Moisture Content: 0.001
- Impurity: 0.001
Superiority
1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so you can trust us. 2, Payment method: for example T/T, Westerm Union,other 3, Excellent Service: Best service and after-sales service to all clients. 1)We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment.. 2)We will ship the goods that you order from us by DHL, UPS, TNT and EUB.We will decided to choose which courier depend on different countries.To find the best way to delivery the goods for you. 3)As usual you can get the goods with in 4-7days.If the goods were lost or not received for other reasons, please contact us immediately. 4,Fast and safe delivery: Sample Order : As usual you can get the goods within 4-7days. We can send it via HKems, HK Air Post, DHL or other methods. We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days. Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our customers and principals. With our high-performance teamwork centers and associated production sites for custom synthesis, we ensure effective professional response and offer extensive applications-related consulting and compliance regulation services. |
Details
Quick Details:
Lincomycin hydrochloride
Alias: Lincomycin HCl, Lincomycin, Lincocin
CAS Registry Number: 859-18-7
Assay: 99%
Formula: C18H34N2O6S. HCl
Molecular Weight: 443.06
EINECS: 212-726-7
Appearance: White powder
Related Substances: Pharmaceutical Grade
Storage: Shading, confined preservation
Usage: Anesthetic Agents, Anti-Allergic Agents
Product Description:
Product nameLincomycin hydrochloride
Other nameLincomycin HCl, Lincomycin, Lincocin
CAS register number859-18-7
Molecular formulaC18H34N2O6S. HCl
Molecular weight443.06
Molecular structure
Assay99%
AppearanceWhite powder
Package25kg/drum or as required
Usagecan be used as pharmaceutical material
Minimum order quantity25kg
ShippingBy express courier
Shipping leading timeWithin 12 hours after receiving the payment
Payment options, MoneyGram, T/T, Banktransfer
PriceNegotiated
Applications:
Lincomycin is a lincosamide antibiotic that comes from the actinomyces Streptomyces lincolnensis. A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality.
Although similar in structure, antibacterial spectrum, and mechanism of action to macrolides, lincomycin is also effective against other organisms including actinomycetes, mycoplasma, and some species of Plasmodium. Intramuscular administration of a single dose of 600 mg of Lincomycin produces average peak serum levels of 11.6 micrograms/ml at 60 minutes, and maintains therapeutic levels for 17 to 20 hours, for most susceptible gram-positive organisms. Urinary excretion after this dose ranges from 1.8 to 24.8 percent (mean: 17.3 percent).
A two-hour intravenous infusion of 600 mg of Lincomycin achieves average peak serum levels of 15.9 micrograms/ml and yields therapeutic levels for 14 hours for most susceptible gram-positive organisms. Urinary excretion ranges from 4.9 to 30.3 percent (mean: 13.8 percent).
The biological half-life after IM or IV administration is 5.4 ± 1.0 hours. The serum half-life of lincomycin may be prolonged in patients with severe impairment of renal function, compared to patients with normal renal function. In patients with abnormal hepatic function, serum half-life may be twofold longer than in patients with normal hepatic function. Hemodialysis and peritoneal dialysis are not effective in removing lincomycin from the serum.
Tissue level studies indicate that bile is an important route of excretion. Significant levels have been demonstrated in the majority of body tissues. Although lincomycin appears to diffuse in the cerebrospinal fluid (CSF), levels of lincomycin in the CSF appear inadequate for the treatment of meningitis.